What significant conflict arose in Kansas as a result of the Kansas-Nebraska Act?

The conflict that arose in Kansas as a result of the Kansas-Nebraska Act is known as Bleeding Kansas. This era, which took place between 1854 and 1859, was marked by a series of violent confrontations between pro-slavery and anti-slavery factions in the Kansas Territory. The Kansas-Nebraska Act, passed in 1854, allowed the people in those territories to decide for themselves whether to allow slavery, a notion known as popular sovereignty. This led to a rush of both pro-slavery and anti-slavery settlers moving into Kansas to influence the decision.

The violence that ensued was fueled by deep-seated tensions over slavery and its expansion into the territories. Both sides engaged in armed conflict, leading to a breakdown of law and order. Events during this time included skirmishes, riots, and even mass murders, making the situation exceptionally chaotic. The term "Bleeding Kansas" became synonymous with this violent struggle, highlighting how deeply divided the nation was over the issue of slavery before the Civil War. This conflict not only foreshadowed Civil War battles but also served as a stark illustration of the increasing polarization of American society regarding slavery.

In contrast, the other options refer to different events or contexts